Chicken Acidic Leucine-rich EGF-like Domain Containing Brain Protein (CALEB), a Neural Member of the EGF Family of Differentiation Factors, Is Implicated in Neurite Formation

@article{Schumacher1997ChickenAL,
  title={Chicken Acidic Leucine-rich EGF-like Domain Containing Brain Protein (CALEB), a Neural Member of the EGF Family of  Differentiation Factors, Is Implicated in Neurite Formation},
  author={Stefan Schumacher and Hansj{\"u}rgen Volkmer and Fritz Buck and Albrecht Otto and Attila Tarnok and Siegfried Roth and Fritz G Rathjen},
  journal={The Journal of Cell Biology},
  year={1997},
  volume={136},
  pages={895 - 906}
}
Chicken acidic leucine-rich EGF-like domain containing brain protein (CALEB) was identified by combining binding assays with immunological screens in the chicken nervous system as a novel member of the EGF family of differentiation factors. cDNA cloning indicates that CALEB is a multidomain protein that consists of an NH2-terminal glycosylation region, a leucine-proline-rich segment, an acidic box, a single EGF-like domain, a transmembrane, and a short cytoplasmic stretch. In the developing… CONTINUE READING