Chick Chorioallantoic Membrane Assay: A 3D Animal Model for Study of Human Nasopharyngeal Carcinoma

Abstract

Nasopharyngeal carcinoma (NPC) is a highly invasive and metastatic head and neck cancer. However, mechanistic study of the invasion and metastasis of NPC has been hampered by the lack of proper in vivo models. We established an in vivo chick embryo chorioallantoic membrane (CAM) model to study NPC tumor biology. We found 100% micro-tumor formation 3 days… (More)
DOI: 10.1371/journal.pone.0130935

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@inproceedings{Xiao2015ChickCM, title={Chick Chorioallantoic Membrane Assay: A 3D Animal Model for Study of Human Nasopharyngeal Carcinoma}, author={Xue Xiao and Xiaoying Zhou and Huixin Ming and Jinyan Zhang and Guangwu Huang and Zhe Zhang and Ping Li and Pierre Busson}, booktitle={PloS one}, year={2015} }