Chewability testing in the development of a chewable tablet for hyperphosphatemia.

  title={Chewability testing in the development of a chewable tablet for hyperphosphatemia.},
  author={Michael Lanz and Jan Baldischweiler and Burkhard Kriwet and Jutta Schill and John Stafford and Georgios Imanidis},
  journal={Drug development and industrial pharmacy},
  volume={40 12},
The official Pharmacopeia does not include a test procedure for the in vitro estimation of the chewability of tablets and publications in the scientific literature on this subject are rare. The purpose of this study was to evaluate a number of different test procedures for assessing chewability, starting from standard breaking force and strength testing and progressing to develop new procedures that simulate the actual chewing action on tablets. A further goal was to apply these test procedures… CONTINUE READING
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