Chemotropic effect of specific target epithelium in the developing mammalian nervous system

@article{Lumsden1986ChemotropicEO,
  title={Chemotropic effect of specific target epithelium in the developing mammalian nervous system},
  author={Andrew G. S. Lumsden and Alun M Davies},
  journal={Nature},
  year={1986},
  volume={323},
  pages={538-539}
}
Developing nerve fibres are guided to their targets by specific directional cues1,2 which are thought to be expressed in the tissues along the route3–7 and may involve the extracellular matrix8–10. Another possibility, that directional cues emanate from the target itself11, is consistent with the recent demonstration of homing behaviour by ectopic retinal ganglion axons12 and our previous demonstration that early trigeminal neurites grow directly to their virgin peripheral target in vitro13… CONTINUE READING

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