Chemotherapy with cisplatin and paclitaxel in locally advanced cervical cancer: has this regimen still a role as neoadjuvant setting?

@article{Moioli2012ChemotherapyWC,
  title={Chemotherapy with cisplatin and paclitaxel in locally advanced cervical cancer: has this regimen still a role as neoadjuvant setting?},
  author={Melita Moioli and Andrea Papadia and Serafina Mammoliti and Elena Pacella and Stefania Menoni and Mario Valenzano Menada and Nicola Ragni},
  journal={Minerva ginecologica},
  year={2012},
  volume={64 2},
  pages={95-107}
}
AIM Neoadjuvant chemotherapy represents a promising alternative to concomitant chemo-radiation therapy in locally advanced cervical cancer patients. The aim of this study was the evaluation of pathologic response rates, toxicity and predictors of response in locally advanced cervical cancer patients treated with neoadjuvant cisplatin and paclitaxel followed by radical surgery. METHODS Fourteen patients with stage IB2 to IIB cervical cancer received three cycles of cisplatin 75 mg/m2 and… CONTINUE READING