Chemotherapy sensitivity testing in human tumours.

@article{Richmond1981ChemotherapyST,
  title={Chemotherapy sensitivity testing in human tumours.},
  author={Herbert Richmond and Richard William Billington},
  journal={Journal of clinical pathology},
  year={1981},
  volume={34 4},
  pages={
          343-50
        }
}
We have attempted to establish in vitro growth in a consecutive series of 245 malignant tumours submitted for routine histopathology. Initially, three disaggregation procedures were used: mechanical separation, digestion by trypsin, and digestion by collagenase. The resulting cell fractions had varying success rates in establishing growth. Abundant epithelial cell growth was achieved in monolayer culture in 63 tumours, and the sensitivity of the cells to cytotoxic agents was tested. There was… CONTINUE READING

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