Chemotherapy of ovarian cancer directed by the human tumor stem cell assay

@article{Alberts1981ChemotherapyOO,
  title={Chemotherapy of ovarian cancer directed by the human tumor stem cell assay},
  author={David S. Alberts and H-S. George Chen and Sydney Salmon and Earl A. Surwit and Laurie Young and Thomas E. Moon and Frank L. Meyskens},
  journal={Cancer Chemotherapy and Pharmacology},
  year={1981},
  volume={6},
  pages={279-285}
}
The human tumor stem cell assay (HTSCA) has been used to study the in vitro sensitivity rates of anticancer drugs used in the treatment of 115 patients with previously untreated and relapsing ovarian cancer. The data from these studies have identified patterns of cross resistance and residual sensitivity between these agents, and have allowed the prospective selection of single agents possessing in vitro activity for the treatment of 32 patients with relapsing disease. cis-Platinum and… CONTINUE READING
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Quantitative association between in vitro and in vivo studies. In: Salmon SE (ed) Cloning of human tumor stem cell, chap 17

  • TE Moon, SE Salmon, HSG Chert, DS Alberts
  • 1980
Highly Influential
4 Excerpts

1980c) In vitro clonogenic assay for predicting response of ovarian cancer to chemotherapy

  • DS Alberts, SE Salmon, HSG Chen
  • Lancet
  • 1980
3 Excerpts

Clinical correlation of drug sensitivity (1980) In: Salmon SE (ed) Cloning of human tumor stem cells

  • SE Salmon
  • 1980
2 Excerpts

Correlative and predictive accuracy of the human tumor stem cell assay (HTSCA) for antieancer drug activity in ovarian (OV) cancer patients (PTS)

  • DS Alberts, SE Salmon, HSG Chen
  • Proc Am Soc Clin Oncol
  • 1980
1 Excerpt

In vitro detection of cross-resistance (XR) and sensitivity (S) in relapsing ovarian cancer (OV) with the human tumor stern cell assay (HTSCA)

  • DS Alberts, SE Salmon, HSG Chen
  • Proe Am Assoc Cancer
  • 1980

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