Chemotherapy of advanced squamous carcinoma of the cervix: a phase I-II study of high-dose cisplatin and cyclophosphamide. A pilot study of the Gynecologic Oncology Group.

@article{Jobson1984ChemotherapyOA,
  title={Chemotherapy of advanced squamous carcinoma of the cervix: a phase I-II study of high-dose cisplatin and cyclophosphamide. A pilot study of the Gynecologic Oncology Group.},
  author={V W Jobson and Hyman Bernard Muss and J. Tate Thigpen and Howard D. Homesley and Brian N. Bundy},
  journal={American journal of clinical oncology},
  year={1984},
  volume={7 4},
  pages={341-5}
}
Sixteen patients with recurrent squamous cell carcinoma of the cervix were treated with a combination of cyclophosphamide and cisplatin to determine a tolerable dose schedule, major adverse effects, and a general estimate of response rate and duration. Toxicity was substantial with a dose of cyclophosphamide 1000 mg/m2 and cisplatin 100 mg/m2 given… CONTINUE READING