Chemotherapy of Plasmodium berghei.

@article{Aviado1969ChemotherapyOP,
  title={Chemotherapy of Plasmodium berghei.},
  author={Domingo M. Aviado},
  journal={Experimental parasitology},
  year={1969},
  volume={25 1},
  pages={
          399-482
        }
}
  • D. Aviado
  • Published 1969
  • Medicine
  • Experimental parasitology
Interactions of the antimalarial drug methylene blue with methemoglobin and heme targets in Plasmodium falciparum: a physico-biochemical study.
TLDR
New insights are provided into the understanding of (i) how MB interacts with hematin-containing targets, (ii) other relevant MB properties in corroboration with the distribution of the three major LMB species as a function of pH, and (iii) how this redox-active cycler induces efficient catalytic reduction of metHb(Fe(III) to hemoglobin( Fe(II) mediated by oxidoreductases.
A quantum chemical investigation of the electronic structure of thionine.
TLDR
The electronic and molecular structure of 3,7-diaminophenothiazin-5-ium dye (thionine) in the electronic ground state and in the lowest excited states is examined and a non-planar minimum is found for the T(3) state with an energy which is very close to the energy of the S(1) minimum in the gas phase.
Phenothiazinium derivatives for pathogen inactivation in blood products.
Das Erythrogramm im Rekonvaleszenzstadium der Nagetiermalaria (Plasmodium berghei) nach Behandlung mit Camolar®
TLDR
In rodent malaria the reticulocytes seem to have a decisive significance for the course of the Erythrogram, in all cases the treatment with Camolar caused a sterilisatio magna.
Biochemie einiger parasitisch lebender Würmer und Protozoen und die Wirkungsweise chemotherapeutisch wichtiger Stoffe
  • H. Metzger
  • Biology
    Zeitschrift für Parasitenkunde
  • 2004
TLDR
Differences in the host and parasite metabolism may give new aspects to synthesize antiparasitics with a low host-toxicity in view of the mode of action of some chemotherapeutics.
Sulphonamides and Sulphones
TLDR
This chapter is focused on the sulphonamides and sulphones1 which are in current use as antimalarial drugs (mostly in combination with pyrimethamine) and the derivatives of dapsone, diformyldapsone and acedapsone.
Rodent Malaria Models
TLDR
The first isolation of rodent malaria was reported by Vincke and Lips (1948) and this isolate was discovered at Keyberg in the former Belgian Congo and named Plasmodium berghei.
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References

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Infections en série par le Plasmodium berghei de Souris blanches traitées
La régression dite spontanée du paludisme a toujours semblé mystérieuse ; toutes les hypothèses émises pour tenter de l’expliquer sont invérifiables et probablement les raisons sont multiples. C’est
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