Chemotherapy-induced peripheral neuropathy: prevention and treatment strategies.

  title={Chemotherapy-induced peripheral neuropathy: prevention and treatment strategies.},
  author={Sherry L. Wolf and Debra L. Barton and Lisa A. Kottschade and Axel F Grothey and Charles M Loprinzi},
  journal={European journal of cancer},
  volume={44 11},
Chemotherapy-induced peripheral neuropathy (CIPN) is a major dose limiting side effect of many commonly used chemotherapeutic agents, including platinum drugs, taxanes, epothilones and vinca alkaloids, and also newer agents such as bortezomib and lenolidamide. Symptom control studies have been conducted looking at ways to prevent or alleviate established CIPN. This manuscript provides a review of studies directed at both of these areas. New evidence strongly suggests that intravenous calcium… CONTINUE READING
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