Chemotherapy in breast cancer patients with brain metastases: have new chemotherapic agents changed the clinical outcome?

@article{Tosoni2008ChemotherapyIB,
  title={Chemotherapy in breast cancer patients with brain metastases: have new chemotherapic agents changed the clinical outcome?},
  author={Alicia Tosoni and Enrico Franceschi and Alba A Brandes},
  journal={Critical reviews in oncology/hematology},
  year={2008},
  volume={68 3},
  pages={212-21}
}
Brain metastasis occurs in 15-40% of cancer patients and is present in approximately 10-16% of patients with metastatic breast disease. However, little is known about prognostic factors enabling the early identification of breast cancer patients at risk of CNS metastases. Therapy for brain metastases should be based on several parameters, such as the assessment of prognostic variables, the extent of neurological and systemic disease, and its chemo-sensitivity to previously administered… CONTINUE READING

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