Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients. Results and conclusions of the multicenter trial ALL-BFM 86.

@article{Reiter1994ChemotherapyI9,
  title={Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients. Results and conclusions of the multicenter trial ALL-BFM 86.},
  author={A. Reiter and Martin Schrappe and W. D. Ludwig and Wolfgang Hiddemann and Siegfried Sauter and Gunter Henze and Martin Zimmermann and Fritz Lampert and Werner Havers and Dietrich Niethammer},
  journal={Blood},
  year={1994},
  volume={84 9},
  pages={3122-33}
}
In trial ALL-BFM 86, the largest multicenter trial of the Berlin-Frankfurt-Münster (BFM) study group for childhood acute lymphoblastic leukemia (ALL), treatment response was used as an overriding stratification factor for the first time. In the previous trial ALL-BFM 83, the in vivo response to initial prednisone treatment was evaluated prospectively. A blast cell count of > or = 1,000/microL peripheral blood after a 7-day exposure to prednisone and one intrathecal dose of methotrexate (MTX… CONTINUE READING
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Clinical Significance of Cytogenetic Studies in Childhood Acute Lymphoblastic Leukemia : Experience of the BFM Tri

  • J Harbott, J Ritterbach, Ludwig W-D, CR Bartram, A Reiter, F Lampert
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