Chemotherapy improves thymoma-associated graft-versus-host-disease-like erythroderma.

  title={Chemotherapy improves thymoma-associated graft-versus-host-disease-like erythroderma.},
  author={Tatsuya Nagano and Yoshikazu Kotani and Kazuyuki Kobayashi and Nanako Tomita and Kyosuke Nakata and Akihiro Sakashita and Yasuhiro Funada and Hiroshi Nagai and Tomonori Itoh and Yoshihiro Nishimura},
  journal={BMJ case reports},
Graft-versus-host-disease (GVHD) with erythroderma can rarely occur in the context of thymoma and is associated with a poor prognosis due to an increased risk of infection-related death. The present study describes a case of a 50-year-old man with malignant thymoma who developed sepsis in addition to skin manifestations similar to that seen in GVHD. This patient experienced marked improvement in skin lesions in response to steroids and combination chemotherapy with carboplatin and paclitaxel… CONTINUE READING