Chemotherapy for medulloblastoma/primitive neuroectodermal tumors of the posterior fossa.

@article{Packer1990ChemotherapyFM,
  title={Chemotherapy for medulloblastoma/primitive neuroectodermal tumors of the posterior fossa.},
  author={Roger J. Packer},
  journal={Annals of neurology},
  year={1990},
  volume={28 6},
  pages={823-8}
}
Chemotherapy has only marginal efficacy in adult malignant brain tumors. In contrast, drug therapy is considerably more effective in medulloblastoma/primitive neuroectodermal tumors (MB/PNET) of the posterior fossa, the most common childhood primary central nervous system tumor. At the time of disease recurrence, a variety of different single agents and drug combinations result in tumor shrinkage and increased survival. The addition of chemotherapy to standard radiotherapy improves the rate and… CONTINUE READING

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