Chemotherapy and the war on cancer

@article{Chabner2005ChemotherapyAT,
  title={Chemotherapy and the war on cancer},
  author={Bruce A. Chabner and Thomas G. Roberts},
  journal={Nature Reviews Cancer},
  year={2005},
  volume={5},
  pages={65-72}
}
The era of chemotherapy began in the 1940s with the first uses of nitrogen mustards and antifolate drugs. Cancer drug development since then has transformed from a low-budget, government-supported research effort to a high-stakes, multi-billion dollar industry. The targeted-therapy revolution has arrived, but the principles and limitations of chemotherapy discovered by the early researchers still apply. This article chronicles the history of modern chemotherapy and identifies remaining… 
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