Chemotherapy and radiation therapy before transhiatal esophagectomy for esophageal carcinoma.

@article{Orringer1990ChemotherapyAR,
  title={Chemotherapy and radiation therapy before transhiatal esophagectomy for esophageal carcinoma.},
  author={Mark B. Orringer and Arlene A. Forastiere and Claudia Perez-Tamayo and Susan G. Urba and Bonnie J. Takasugi and Judith Bromberg},
  journal={The Annals of thoracic surgery},
  year={1990},
  volume={49 3},
  pages={
          348-54; discussion 354-5
        }
}
Recent efforts to improve survival in patients with esophageal carcinoma have combined both systemic and local therapy. From October 1985 to October 1987, 43 patients with local-regional esophageal cancer (adenocarcinoma in 21, squamous cell in 22) were treated with cisplatin, vinblastine, and 5-fluorouracil chemotherapy concurrent with 4,500 cGy radiation therapy for 21 days before transhiatal esophagectomy 3 weeks later. Two patients died of chemotherapy/radiation therapy toxicity. Forty-one… CONTINUE READING

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