Chemotherapy and operation for invasive thymoma.

  title={Chemotherapy and operation for invasive thymoma.},
  author={Federico Rea and Francesco Sartori and Monica Loy and Francesco Calabr{\`o} and Adriano Fornasiero and O Daniele and Guiseppe Altavilla},
  journal={The Journal of thoracic and cardiovascular surgery},
  volume={106 3},
Sixteen patients with invasive thymoma (stage III and stage IVA) were treated with chemotherapy and then operation. All tumors were considered nonresectable after first staging, and patients were treated with the following chemotherapy in 4-day courses, administered intravenously: cisplatin (50 mg/m2) and doxorubicin (40 mg/m2) on day 1, vincristine (0.6 mg/m2) on day 3, and cyclophosphamide (700 mg/m2) on day 4. The courses were repeated every 3 weeks, and toxic effects were well tolerated… CONTINUE READING


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