Chemotherapy-Induced Cardiotoxicity

@article{Shaikh2012ChemotherapyInducedC,
  title={Chemotherapy-Induced Cardiotoxicity},
  author={Amir Y. Shaikh and J. Shih},
  journal={Current Heart Failure Reports},
  year={2012},
  volume={9},
  pages={117-127}
}
  • Amir Y. Shaikh, J. Shih
  • Published 2012
  • Medicine
  • Current Heart Failure Reports
  • Anthracycline-based chemotherapeutics have long been recognized as effective agents for treating a wide range of malignancies. However, their use is not without significant adverse cardiotoxic side effects. Strategies for prevention involve limiting free-radical production and subsequent cardiac myocyte damage. Dexrazoxane remains the most widely studied cardioprotective medication. Alternative agents may reduce cardiotoxicity but may still cause significant cardiovascular problems. The role of… CONTINUE READING
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