Chemotaxis and phagocytosis in neutrophils is independent of coronin 1.


The WD repeat protein family member coronin 1 is exclusively expressed in leukocytes, where it colocalizes with the cortical cytoskeleton. Although initially coronin 1 was believed to regulate F-actin dynamics such as leukocyte motility, phagocytosis, and membrane ruffling, recent work showed that in macrophages, T cells, and B cells, coronin 1 is… (More)
DOI: 10.4049/jimmunol.0801812

5 Figures and Tables


  • Presentations referencing similar topics