Chemotactic response of Brugia pahangi infective larvae to jird serum in vitro

@article{Gunawardena2003ChemotacticRO,
  title={Chemotactic response of Brugia pahangi infective larvae to jird serum in vitro},
  author={Nipul Kithsiri Gunawardena and Yasunori Fujimaki and Yoichi Aoki},
  journal={Parasitology Research},
  year={2003},
  volume={90},
  pages={337-342}
}
The Brugia pahangi infective larval response to jird serum was studied using an agar plate assay. Larvae placed onto the agar remained at the same place for 60 min. Once the larvae were stimulated by serum, more than 95% oriented towards the serum and reached it within few minutes. This larval response was inhibited by an activator of phosphodiesterase (imidazole), adenylate cyclase inhibitors (SQ22536 and MDL-12330A) and protein kinase A inhibitor. An inhibitor of phosphodiesterase (IBMX), an… CONTINUE READING