Chemotactic and candidacidal responses of rabbit alveolar macrophages during postnatal development and the modulating roles of surfactant in these responses.

@article{Zeligs1984ChemotacticAC,
  title={Chemotactic and candidacidal responses of rabbit alveolar macrophages during postnatal development and the modulating roles of surfactant in these responses.},
  author={Barbara J. Zeligs and Lata S Nerurkar and Joseph A. Bellanti},
  journal={Infection and immunity},
  year={1984},
  volume={44 2},
  pages={379-85}
}
Chemotactic responses of alveolar macrophages from 1-, 7-, and 28-day-old rabbits to various concentrations of endotoxin-activated serum and n-formyl-methionyl-phenylalanine were tested utilizing both blind well and agarose plate assay systems. A dramatic increase in both the chemotactic response and responsiveness to various concentrations of chemoattractant was observed during postnatal maturation. The pattern of result was similar with both methods of assay. An age-related increase was also… CONTINUE READING
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