Chemostat modeling of Escherichia coli persistence in conventionalized mono-associated and streptomycin-treated mice.

@article{Rang2001ChemostatMO,
  title={Chemostat modeling of Escherichia coli persistence in conventionalized mono-associated and streptomycin-treated mice.},
  author={Camilla Ulla Rang and Tore Midtvedt and S{\o}ren Molin and Lin Chao},
  journal={Canadian journal of microbiology},
  year={2001},
  volume={47 1},
  pages={
          86-90
        }
}
We have previously shown that Escherichia coli BJ4 has similar doubling time in mice that are mono-associated (having only the inoculated E. coli BJ4) or streptomycin-treated (having mainly gram-positive bacteria plus the inoculated E. coli BJ4). We also showed that when the mice were conventionalized (fed cecum homogenate from conventional mice or ones with a complete microbial flora), the introduction of complete flora in both cases increased the in vivo doubling time, while decreasing the… CONTINUE READING