Chemoradiotherapy of newly diagnosed glioblastoma with intensified temozolomide.

@article{Weiler2010ChemoradiotherapyON,
  title={Chemoradiotherapy of newly diagnosed glioblastoma with intensified temozolomide.},
  author={Markus Weiler and Christian Hartmann and Dorothee Wiewrodt and Ulrich Herrlinger and Thierry Gorlia and Oliver Baehr and Richard Meyermann and Michael G. Bamberg and Marcos Tatagiba and Andreas von Deimling and Michael Weller and Wolfgang Wick},
  journal={International journal of radiation oncology, biology, physics},
  year={2010},
  volume={77 3},
  pages={
          670-6
        }
}
PURPOSE To evaluate the toxicity and efficacy of chemoradiotherapy with temozolomide (TMZ) administered in an intensified 1-week on/1-week off schedule plus indomethacin in patients with newly diagnosed glioblastoma. PATIENTS AND METHODS A total of 41 adult patients (median Karnofsky performance status, 90%; median age, 56 years) were treated with preirradiation TMZ at 150 mg/m(2) (1 week on/1 week off), involved-field radiotherapy combined with concomitant low-dose TMZ (50 mg/m(2… CONTINUE READING

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