Chemoprotective effects of carnosine against genotoxicity induced by cyclophosphamide in mice bone marrow cells

@article{Naghshvar2012ChemoprotectiveEO,
  title={Chemoprotective effects of carnosine against genotoxicity induced by cyclophosphamide in mice bone marrow cells},
  author={Farshad Naghshvar and Shahrzad Mohseni Abianeh and Saeb Ahmadashrafi and Seyed Jalal Hosseinimehr},
  journal={Cell Biochemistry and Function},
  year={2012},
  volume={30}
}
The protective effects of carnosine as a natural dipeptide were investigated in mouse bone marrow cells against genotoxicity induced by cyclophosphamide. Mice were injected with solutions of carnosine at three different doses (10, 50 and 100 mg kg–1 bw) for five consecutive days. On the fifth day of treatment, mice were injected cyclophosphamide and killed after 24 h. The frequency of micronuclei in polychromatic erythrocytes and the ratio of polychromatic erythrocyte/polychromatic erythrocyte… 

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  • S. Quita
  • Chemistry, Medicine
    Electronic physician
  • 2016
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