Chemopreventive Effects of 24 R , 25-Dihydroxyvitamin D 3 , a Vitamin D 3 Derivative , on Glandular Stomach Carcinogenesis Induced in Rats by jV-Methyl-W-nitro-A /-nitrosoguanidine and Sodium Chloride 1

@inproceedings{Ikezaki2006ChemopreventiveEO,
  title={Chemopreventive Effects of 24 R , 25-Dihydroxyvitamin D 3 , a Vitamin D 3 Derivative , on Glandular Stomach Carcinogenesis Induced in Rats by jV-Methyl-W-nitro-A /-nitrosoguanidine and Sodium Chloride 1},
  author={Shinichiro Ikezaki and Akiyoshi Nishikawa and Fumio Furukawa and Zen-yo Tanakamaru and H Kim and Hideki Mori and Michihito Takahashi},
  year={2006}
}
The modifying effects of 24A,25-dihydroxyvitamin D, [24R,25(OH)2D3], a vitamin I), derivative, on glandular stomach carcinogenesis were investigated in male Wistar rats by Af-methyl-JV'-nitro-A'-nitrosoguanidine (MNNG) and sodium chloride exposure during the postinitiation phase. A total of 130 male 6-week-old rats was divided into five groups. Groups 1-3 (consisting of 30 rats/group) were given MNNG in drinking water at a concentration of 100 ppm and were simultaneously fed a diet supplemented… CONTINUE READING