Chemoprevention of lung cancers: lessons from CARET, the beta-carotene and retinol efficacy trial, and prospects for the future

@article{Omenn2007ChemopreventionOL,
  title={Chemoprevention of lung cancers: lessons from CARET, the beta-carotene and retinol efficacy trial, and prospects for the future},
  author={Gilbert S. Omenn},
  journal={European Journal of Cancer Prevention},
  year={2007},
  volume={16},
  pages={184-191}
}
  • G. Omenn
  • Published 1 June 2007
  • Medicine
  • European Journal of Cancer Prevention
The objective of this paper was to review the strategies for lung cancer chemoprevention. [] Key Method A retrospective assessment of the major findings from the most informative lung cancer chemoprevention clinical trials [alpha-tocopherol (vitamin E), beta-carotene trial and beta-carotene and retinol efficacy trial] was employed. Both trials and many others showed no benefit from what was once the prime candidate for lung cancer chemoprevention, beta-carotene. Furthermore, both trials found that beta…

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