Chemoprevention of lung cancer--from biology to clinical reality.

  title={Chemoprevention of lung cancer--from biology to clinical reality.},
  author={Ralph C Winterhalder and Fred R Hirsch and Georgia Kotantoulas and Wilbur A. Franklin and Paul A. Bunn},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  volume={15 2},
Lung cancer is the commonest cause of cancer death in developed countries and throughout the world. Cigarette smoking is the main risk factor for lung cancer and ex-smokers today comprise approximately 50% of all new lung cancer cases. Chemoprevention builds on the concepts of field of cancerization and multistep carcinogenesis and can be defined as the use… CONTINUE READING