Chemoprevention of breast cancer

  title={Chemoprevention of breast cancer},
  author={Powel H. Brown and Scott Michael Lippman},
  journal={Breast Cancer Research and Treatment},
Despite a recent trend toward improvement in the U.S. breast cancer mortality rate, breast cancer incidence (182,800 new cases anticipated in 2000) and mortality figures (over 40,800 anticipated deaths) remain the highest and second highest, respectively, of all cancers in U.S. women. In 1998, the selective-estrogen-receptor-modulator (SERM) tamoxifen achieved positive results in the Breast Cancer Prevention Trial (BCPT), leading to the Food and Drug Administration (FDA) approval of tamoxifen… CONTINUE READING
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