Chemomyectomy of the orbicularis oculi muscles for the treatment of localized hemifacial spasm.

@article{Wirtschafter1994ChemomyectomyOT,
  title={Chemomyectomy of the orbicularis oculi muscles for the treatment of localized hemifacial spasm.},
  author={Jonathan D. Wirtschafter},
  journal={Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society},
  year={1994},
  volume={14 4},
  pages={199-204}
}
OBJECTIVE To report our experience with doxorubicin chemomyectomy as an alternative to other treatments for hemifacial spasm (HFS). DESIGN A prospective, open study Phase I clinical trial of chemomyectomy. SETTING A hospital-based, referral neuro-ophthalmology and oculoplastic service. PATIENTS AND METHODS Repeated (1-6, median: 4) local injections of doxorubicin were given in the eyelids of 8 patients (5 men, 3 women, average age: 71). MAIN OUTCOME MEASURES Eyelid strength, self… CONTINUE READING