Chemometrics optimization of six antihistamines separations by capillary electrophoresis with electrochemiluminescence detection.

This work expanded the knowledge of the use of chemometric experimental design in optimizing of six antihistamines separations by capillary electrophoresis with electrochemiluminescence detection. Specially, central composite design was employed for optimizing the three critical electrophoretic variables (Tris-H(3)PO(4) buffer concentration, buffer pH value… CONTINUE READING