Chemometric modeling of breast cancer associated carbonic anhydrase IX inhibitors belonging to the ureido-substituted benzene sulfonamide class.

Abstract

Ureido-substituted benzene sulfonamides are the most important class of CA inhibitors which significantly inhibited the formation of primary tumors and metastases. Here, we present quantitative structure activity relationships (QSAR) study on a pool of 27 such inhibitors. A heuristic algorithm selected the best multiple linear regression (MLR) equation… (More)
DOI: 10.3109/14756366.2013.864652

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Cite this paper

@article{Singh2014ChemometricMO, title={Chemometric modeling of breast cancer associated carbonic anhydrase IX inhibitors belonging to the ureido-substituted benzene sulfonamide class.}, author={Shalini Singh and Claudiu T. Supuran}, journal={Journal of enzyme inhibition and medicinal chemistry}, year={2014}, volume={29 6}, pages={877-83} }