Chemokines of the alpha, beta-subclass inhibit human basophils' responsiveness to monocyte chemotactic and activating factor/monocyte chemoattractant protein-1.

@article{Kuna1995ChemokinesOT,
  title={Chemokines of the alpha, beta-subclass inhibit human basophils' responsiveness to monocyte chemotactic and activating factor/monocyte chemoattractant protein-1.},
  author={Piotr Kuna and Sesha R. Reddigari and Daniel Ruciński and Thomas J. Schall and Allen P. Kaplan},
  journal={The Journal of allergy and clinical immunology},
  year={1995},
  volume={95 2},
  pages={574-86}
}
Monocyte chemotactic and activating factor (MCAF) is the most potent cytokine that activates basophils to release histamine. The response of human basophils to either simultaneous or sequential addition of the chemokines RANTES, macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta, platelet factor (PF)4, connective tissue activating peptide III (CTAP… CONTINUE READING