Chemokines in vascular dysfunction and remodeling.

  title={Chemokines in vascular dysfunction and remodeling.},
  author={Andreas Schober},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  volume={28 11},
Vascular remodeling stands for structural changes of the vessel wall in response to various noxious stimuli, which results in reorganization of the vessel wall architecture. Luminal narrowing because of neointima formation and constrictive remodeling leading to hypoperfusion is the most relevant clinical effect. Smooth muscle cell (SMC) accumulation, inflammatory cell recruitment, and endothelial regeneration are the critical parts in obstructive vascular remodeling. Chemokines and chemokine… CONTINUE READING
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