Chemokines and the Homing of Dendritic Cells to the T Cell Areas of Lymphoid Organs


A quarter of a century ago, it was proposed that veiled cells in the lymph were antigen-bearing Langerhans' cells (LCs) en route to the LN T cell area (1, 2). Extensive investigations have since established that LCs are immature dendritic cells (DCs) and that insults to the skin—including exposure to contact sensitizers, bacteria, or UV light— cause many of… (More)


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