Chemokine upregulation follows cytokine expression in chronic relapsing experimental autoimmune encephalomyelitis.

@article{Glabinski2003ChemokineUF,
  title={Chemokine upregulation follows cytokine expression in chronic relapsing experimental autoimmune encephalomyelitis.},
  author={Andrzej Glabinski and Bartosz Bielecki and Richard M Ransohoff},
  journal={Scandinavian journal of immunology},
  year={2003},
  volume={58 1},
  pages={81-8}
}
Chronic relapsing experimental autoimmune encephalomyelitis (ChREAE) is an autoimmune disease of the central nervous system (CNS) induced by CNS myelin components. In the early active stage, both ChREAE and multiple sclerosis (MS) are characterized by the presence of perivascular inflammatory cuffs disseminated in the CNS. There is growing evidence that chemoattractant cytokines (chemokines) play an important role in this process. The main goal of the present study was to analyse the hypothesis… CONTINUE READING