Chemokine receptors and melanoma metastasis.

@article{Murakami2004ChemokineRA,
  title={Chemokine receptors and melanoma metastasis.},
  author={Takashi Murakami and Adela R. Cardones and Sam Hwang},
  journal={Journal of dermatological science},
  year={2004},
  volume={36 2},
  pages={71-8}
}
Cancer metastasis is the end result of a complex series of biologic events that leads to the formation of clinically significant secondary tumors at distant sites. The sites of distant metastasis are not random since certain tumors show a tendency to develop metastases in specific organs. Human melanoma, for example, demonstrates frequent metastasis to brain, lungs, lymph nodes, and skin. Herein, we review the evidence that suggests that a limited number of chemokine receptors may play critical… CONTINUE READING

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