Chemokine receptor expression on resident and inflammatory cells in the brain of macaques with simian immunodeficiency virus encephalitis.

@article{Westmoreland1998ChemokineRE,
  title={Chemokine receptor expression on resident and inflammatory cells in the brain of macaques with simian immunodeficiency virus encephalitis.},
  author={Susan. V. Westmoreland and James B. Rottman and Kenneth Williams and Andrew A Lackner and Vito G. Sasseville},
  journal={The American journal of pathology},
  year={1998},
  volume={152 3},
  pages={659-65}
}
Although the mechanisms of human immunodeficiency virus (HIV) neuroinvasion, neuronal injury, and subsequent development of HIV-1-associated AIDS dementia complex are not fully understood, a correlation between monocyte/macrophage infiltrates in the brain and neurological disease exists. In light of the many potential roles that chemokines and chemokine receptors may play in HIV neuropathogenesis, we sought to describe their pattern of expression in the SIV-infected rhesus macaque model of HIV… CONTINUE READING

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