Chemokine receptor CX3CR1 regulates renal interstitial fibrosis after ischemia-reperfusion injury.

@article{Furuichi2006ChemokineRC,
  title={Chemokine receptor CX3CR1 regulates renal interstitial fibrosis after ischemia-reperfusion injury.},
  author={Kengo Furuichi and J Gao and Philip G. M. Murphy},
  journal={The American journal of pathology},
  year={2006},
  volume={169 2},
  pages={372-87}
}
Transient renal ischemia induces both inflammatory and fibrotic processes and is a major cause of acute and chronic renal insufficiency. Study of ischemia-reperfusion injury in gene-targeted mice has identified multiple factors responsible for inflammation, whereas mechanisms underlying fibrosis remain poorly defined. Here we demonstrate by both gene… CONTINUE READING