Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues

@article{Debes2005ChemokineRC,
  title={Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues},
  author={Gudrun F Debes and Carrie N. Arnold and Alan J. Young and Stefan Krautwald and Martin Lipp and John B. Hay and Eugene C. Butcher},
  journal={Nature Immunology},
  year={2005},
  volume={6},
  pages={889-894}
}
Lymphocytes travel throughout the body to carry out immune surveillance and participate in inflammatory reactions. Their path takes them from blood through tissues into lymph and back to blood. Molecules that control lymphocyte recruitment into extralymphoid tissues are well characterized, but exit is assumed to be random. Here, we showed that lymphocyte… CONTINUE READING