Chemokine networks and breast cancer metastasis.

  title={Chemokine networks and breast cancer metastasis.},
  author={Antoine E Karnoub and Robert A Weinberg},
  journal={Breast disease},
Chemokines have been initially characterized as chemoattractants for leukocytes infiltrating into inflamed tissues. However, over the past few years, accumulating evidence has described the critical involvement of this superfamily of intercellular signaling proteins in a variety of biological processes, which include embryogenesis, organogenesis, and tissue homeostasis. Moreover, recent work has demonstrated novel roles for chemokines and their receptors in regulating various aspects of the… CONTINUE READING

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