Chemokine monokine induced by IFN-gamma/CXC chemokine ligand 9 stimulates T lymphocyte proliferation and effector cytokine production.

@article{Whiting2004ChemokineMI,
  title={Chemokine monokine induced by IFN-gamma/CXC chemokine ligand 9 stimulates T lymphocyte proliferation and effector cytokine production.},
  author={David Whiting and George R. Hsieh and James J. Yun and Anamika Banerji and William Yao and Michael C. Fishbein and John A Belperio and Robert M. Strieter and Benjamin Bonavida and Abbas A Ardehali},
  journal={Journal of immunology},
  year={2004},
  volume={172 12},
  pages={7417-24}
}
Monokine induced by IFN-gamma (MIG; CXC chemokine ligand (CXCL)9) is important in T lymphocyte recruitment in organ transplantation. However, it is not known whether this chemokine, in addition to its chemotactic properties, exerts any effect on T lymphocyte effector functions. For in vivo studies, we used a previously characterized murine model of chronic rejection. The recipient mice were treated with anti-MIG/CXCL9 Ab; graft-infiltrating cells were analyzed for IFN-gamma production. For in… CONTINUE READING