Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain.

@article{Glabinski1996ChemokineMC,
  title={Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain.},
  author={Andrzej Glabinski and Vijayabalan Balasingam and Marie Tani and Steven L. Kunkel and Robert M. Strieter and V. Wee Yong and Richard M Ransohoff},
  journal={Journal of immunology},
  year={1996},
  volume={156 11},
  pages={4363-8}
}
By 24 h after mechanical trauma to the cerebral cortex, astroglial reaction begins and injury sites are infiltrated by activated mononuclear phagocytes derived from blood-borne monocytes and endogenous microglia. There is little information about cellular interactions between astrocytes and leukocytes during this process. We previously showed that murine astrocytes produce chemokines including monocyte chemoattractant protein-1 (MCP-1) during experimental autoimmune encephalomyelitis. In this… CONTINUE READING
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