Chemokine homolog of molluscum contagiosum virus: sequence conservation and expression.

@article{Bugert1998ChemokineHO,
  title={Chemokine homolog of molluscum contagiosum virus: sequence conservation and expression.},
  author={Joachim Jakob Bugert and Claudia Lohm{\"u}ller and Inger K. Damon and Bernard Moss and Gholamreza Darai},
  journal={Virology},
  year={1998},
  volume={242 1},
  pages={
          51-9
        }
}
An analysis of the complete Molluscum contagiosum virus (MCV-1) genome sequence revealed a 104-amino-acid open reading frame (MC148R) that is structurally related to the beta (CC) family of chemokines. The predicted MCV chemokine homolog (MCCH) has a deletion in the NH2-terminal activation domain, suggesting the absence of chemoattractant activity. The principal objectives of the present study were to determine whether: (i) MCCH is conserved in independent isolates of MCV-1 and MCV-2; (ii) MCCH… CONTINUE READING

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