Chemokine expression in rheumatoid arthritis (RA): evidence of RANTES and macrophage inflammatory protein (MIP)-1 beta production by synovial T cells.

@article{Robinson1995ChemokineEI,
  title={Chemokine expression in rheumatoid arthritis (RA): evidence of RANTES and macrophage inflammatory protein (MIP)-1 beta production by synovial T cells.},
  author={Elliot Robinson and Edward Clark Keystone and Thomas J. Schall and Nancy A. Gillett and Eleanor N Fish},
  journal={Clinical and experimental immunology},
  year={1995},
  volume={101 3},
  pages={398-407}
}
Earlier studies from this laboratory provided evidence for restricted cytokine expression in the T cell population in RA tissues. Specifically, IL-2, IL-4, IL-6 and interferon-gamma (IFN-gamma) gene expression levels were low. The selective chemoattractant and activation effects of chemokines on leucocytes identify them as potentially ideal candidates in mediating selective inflammatory processes in RA. Accordingly, we undertook studies to examine constitutive chemokine gene expression in RA… CONTINUE READING