Chemokine Involvement in Fetal and Adult Wound Healing.

  title={Chemokine Involvement in Fetal and Adult Wound Healing.},
  author={S. Prathab Balaji and Carey L. Watson and Rajeev Ranjan and Alice King and Paul L. Bollyky and Sundeep G. Keswani},
  journal={Advances in wound care},
  volume={4 11},
Significance: Fetal wounds heal with a regenerative phenotype that is indistinguishable from surrounding skin with restored skin integrity. Compared to this benchmark, all postnatal wound healing is impaired and characterized by scar formation. The biologic basis of the fetal regenerative phenotype can serve as a roadmap to recapitulating regenerative repair in adult wounds. Reduced leukocyte infiltration, likely mediated, in part, through changes in the chemokine milieu, is a fundamental… CONTINUE READING
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