Chemoenzymatic taxanes approach using both enantiomers of the same building block. 2. Taxol CD ring unit.

Abstract

[reaction: see text] The enantioselective synthesis of the Taxol CD ring unit has been achieved starting from an enantiopure building block, the enantiomer of those previously utilized in the synthesis of the A ring unit. The key features of the present synthesis are astute use of both enantiomers of the same building block and complete control in the construction of five consecutive chiral centers.

Cite this paper

@article{Uttaro2005ChemoenzymaticTA, title={Chemoenzymatic taxanes approach using both enantiomers of the same building block. 2. Taxol CD ring unit.}, author={Jean-Pierre Uttaro and G{\'e}rard Audran and Honor{\'e} Monti}, journal={The Journal of organic chemistry}, year={2005}, volume={70 9}, pages={3484-9} }