Chemoembolization combined with radiofrequency ablation for patients with hepatocellular carcinoma larger than 3 cm: a randomized controlled trial.


CONTEXT Transarterial chemoembolization (TACE) combined with radiofrequency ablation (RFA) therapy has been used for patients with large hepatocellular carcinoma tumors, but the survival benefits of combined treatment are not known. OBJECTIVE To compare rates of survival of patients with large hepatocellular carcinoma tumors who received treatment with… (More)
DOI: 10.1001/jama.299.14.1669

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