Chemoconvulsant seizures: Advantages of focally-evoked seizure models

  title={Chemoconvulsant seizures: Advantages of focally-evoked seizure models},
  author={D. K.GalePh.},
  journal={The Italian Journal of Neurological Sciences},
Studies of short and long-term changes in regional metabolism, blood flow, gene expression (including immediate early genes and genes for neurotrophic factors), sprouting and cell death following seizures are pivotal to an under-standing of the neural networks responsible for the generation of seizures. At the same time, this information forms a basis for understanding the pathophysiology associated with chronic, recurrent seizures. Systemic chemoconvulsant seizure models, produced by… CONTINUE READING