Chemistry of zerumbone. 2. Regulation of ring bond cleavage and unique antibacterial activities of zerumbone derivatives.

@article{Kitayama2001ChemistryOZ,
  title={Chemistry of zerumbone. 2. Regulation of ring bond cleavage and unique antibacterial activities of zerumbone derivatives.},
  author={Takashi Kitayama and Kanako Yamamoto and Ryutaro Utsumi and Maki Takatani and Richard K. Hill and Y Kawai and Seiji Sawada and Tetsuji Okamoto},
  journal={Bioscience, biotechnology, and biochemistry},
  year={2001},
  volume={65 10},
  pages={2193-9}
}
Further investigation of the chemistry of the eleven-membered cyclic sesquiterpene, zerumbone, the major component of the wild ginger, Zingiber zerumbet Smith, has revealed a new selective epoxidation process, a further example of a novel Favorskii-initiated double ring contraction, and a regiospecific fragmentation of zerumbone dibromide derivatives. Several zerumbone derivatives were found to be selective inhibitors of the growth of gram-positive bacteria.