Chemistry and Health of Olive Oil Phenolics

  title={Chemistry and Health of Olive Oil Phenolics},
  author={Sara Cicerale and Xavier A. Conlan and Andrew J Sinclair and Russell S J Keast},
  journal={Critical Reviews in Food Science and Nutrition},
  pages={218 - 236}
The Mediterranean diet is associated with a lower incidence of atherosclerosis, cardiovascular disease, and certain types of cancer. The apparent health benefits have been partially attributed to the dietary consumption of virgin olive oil by Mediterranean populations. Most recent interest has focused on the biologically active phenolic compounds naturally present in virgin olive oils. Studies (human, animal, in vivo and in vitro) have shown that olive oil phenolics have positive effects on… 
Biological Activities of Phenolic Compounds Present in Virgin Olive Oil
Current knowledge on the bioavailability and biological activities of olive oil phenolic compounds is summarized to aid in explaining reduced mortality and morbidity experienced by people consuming a traditional Mediterranean diet.
The Health Benefiting Mechanisms of Virgin Olive Oil Phenolic Compounds
The evidence presented in the review concludes that oleurepein, hydroxytyrosol and oleocanthal have potent pharmacological activities in vitro and in vivo; however, intervention studies with biologically relevant concentrations of these phenolic compounds are required.
Olive oil and health effects: from epidemiological studies to the molecular mechanisms of phenolic fraction
Supporting the protective effects of olive oil against degenerative diseases found in large cohorts monitored in Southern European countries is found.
Health effects of olive oil polyphenols: recent advances and possibilities for the use of health claims.
This review discusses the health effects of olive oil phenols along with the possibilities of communicating these effects on food labels and the evidence is already strong enough to enable the legal use of health claims on foods.
Virgin Olive Oil, A Rich Source of Functional Bioactive Compounds in the Promotion of Human Health: An Overview
The health benefits discussed in this article support the prospective health benefits acquired from VOO as a possible candidate in developing pharmaceutical preparations and nutraceutical or functional foods for a variety of pathological disorders.
Positive Health Effects of Olive Oil
Olive oil is the main source of fat in the Mediterranean diet. Although the use of olive oil has a long history, in recent decades it has experienced a full bloom all over the world. The consumption
Antimicrobial, antioxidant and anti-inflammatory phenolic activities in extra virgin olive oil.
An up-date of olive oil phenols in inflammation and cancer: molecular mechanisms and clinical implications.
The chemistry, bioavailability and pharmacokinetic characteristics of OO polyphenols are reviewed to provide the reader an up-date of their putative antioxidant, anti-inflammatory and anti-cancer activities as well as the plausible action mechanisms involved.
Review Summary Foods have been used historically, across cultures and for centuries, in treating disease and curing illness, owing to the role of antioxidants found naturally in foods. Also, it is


The phenolic compounds of olive oil: structure, biological activity and beneficial effects on human health
This review focuses on recent works analysing the relationship between the structure of olive oil polyphenolic compounds and their antioxidant activity, which is related to the development of atherosclerosis and cancer, and to anti-inflammatory and antimicrobial activity.
Tyrosol Bioavailability in Humans after Ingestion of Virgin Olive Oil
Results from epidemiological studies support the relationship between the consumption of phenolic-rich food and a low incidence of coronary heart disease (1)(2). The lower incidences of coronary
Antioxidant and other biological activities of phenols from olives and olive oil
Findings demonstrate that olive oil phenolics are powerful antioxidants, both in vitro and in vivo, and possess other potent biological activities that could partially account for the observed healthful effects of the Mediterranean diet.
Major phenolic compounds in olive oil: metabolism and health effects.
The role of virgin olive oil components in the modulation of endothelial function.
Olive oil and the cardiovascular system.
  • M. Covas
  • Biology
    Pharmacological research
  • 2007
Postprandial LDL phenolic content and LDL oxidation are modulated by olive oil phenolic compounds in humans.
Atherosclerosis--epidemiological studies on the health effects of a Mediterranean diet.
In conclusion, epidemiological studies and intervention trials suggest that the Cretan Mediterranean diet lowers the risk of coronary heart disease.
Evidence of postprandial absorption of olive oil phenols in humans.
The findings suggest that phenolic compounds in olive oil are absorbed from the intestine, though not through a pathway dependent on chylomicron formation, and may exert a significant antioxidant effect in vivo, probably in the postprandial phase.